The relationship between the consumption of alcohol and a range of violent crimes, including homicide, is overwhelmingly acknowledged by criminologists. Less is known about the specifics of this relationship—in particular, whether the worst alcohol related violence occurs in private, or in public settings such as Australia’s expanding night-time leisure areas. This study finds no evidence of a substantial concentration of homicides in specific night-time leisure areas. Homicides are, however, both directly and indirectly related to the night-time economy, with indirectly related incidents outweighing others. This finding affirms the need to persist with strategies to limit intoxication associated with night-time leisure, and further explore ways to control the sale of and access to alcohol in the general community.